A Review Of Crest
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Mononuclear infiltration likely precedes fibrosis of tissues. Histologic specimens from individuals with illness period of below 2 decades demonstrate mononuclear infiltration close to blood vessels and dermal appendages.
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The relationship of Raynaud phenomenon to esophageal dysmotility is interesting. Cold-induced vasospasm from the palms also results in esophageal dysmotility, and reversal of the vasospasm with reserpine reverses both of those peripheral Raynaud phenomenon and abnormalities in esophageal motility (as documented by Sjogren [30] in 1994); nonetheless, people with Main Raynaud phenomenon will not tend to get esophageal dysmotility. Hence, the significance of these observations stays to become identified. [32]
Arteries from scleroderma individuals have noticeably improved sensitivity to alpha2-adenoreceptor–mediated vasoconstriction. Whether or not that is a consequence or explanation for endothelial cell damage and dysfunction is unclear.
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, 30 Aug. 2021 These instance sentences are picked routinely from various online news sources to mirror latest use from the phrase 'crest.' Views expressed from the illustrations don't symbolize the belief of Merriam-Webster or its read more editors. Mail us suggestions. See A lot more
The consequences of esophageal dysmotility are reflux and its troubles. The minimized LES stress in patients with scleroderma probable permits acid reflux, which is exacerbated by delayed clearance of acid with the esophagus as a result of irregular distal motility.
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1a : a showy tuft or approach on the head of an animal and particularly a chicken — see chook illustration b : the plume or pinpointing emblem worn on a knight's helmet also : the top of a helmet c(one) : a heraldic representation of the crest (2) : a heraldic machine depicted previously mentioned the escutcheon (see escutcheon perception 1) but not on a helmet (three) : coat of arms sense 2a d : a ridge or prominence on a Element of an animal entire body two : some thing suggesting a crest particularly in remaining an upper prominence, edge, or limit: like a : peak especially : the very best line of a mountain or hill b : the ridge of a roof c : the highest of the wave 3a : a high level of an motion or system and especially of one that is rhythmic b : climax, culmination on the crest of his fame crest